Product Name: Cefradine
CAS: 38821-53-3

Cefradine is a first-generation cephalosporin antibiotic with broad-spectrum antibacterial activity. It is mainly used to treat various infections caused by susceptible bacteria and is commonly used in both veterinary and human medicine. Cefradine works by inhibiting bacterial cell wall synthesis and is effective against a variety of Gram-positive bacteria and some Gram-negative bacteria.

Pharmacological Effects:
1. Cefradine belongs to the cephalosporin class of antibiotics. It inhibits bacterial cell wall synthesis, causing bacterial cell wall fragility and disintegration, achieving bactericidal effects.
2. Has good antibacterial activity against Gram-positive bacteria such as Streptococcus, Staphylococcus, Pneumococcus, as well as some Gram-negative bacteria like Escherichia coli.

Indications:
- Respiratory tract infections: Used to treat upper respiratory tract infections (such as pharyngitis, tonsillitis) and lower respiratory tract infections (such as bronchitis, pneumonia) caused by susceptible bacteria.
- Urinary tract infections: Suitable for urinary tract infections such as cystitis, pyelonephritis.
- Skin and soft tissue infections: Suitable for treating skin and soft tissue infections caused by bacterial infections.
- Bone and joint infections: Used to treat bacterial bone and joint infections such as osteomyelitis.

Administration:
- Cefradine is usually administered as oral capsules, tablets, or injections.
- Dosage and course of treatment should be adjusted according to the severity of infection and patient condition. It is recommended to follow the professional guidance of a physician or veterinarian.

Pharmacokinetics:
- Cefradine is well absorbed in the gastrointestinal tract, rapidly reaching peak plasma concentration after oral administration, with a half-life of approximately 1 hour.
- Excreted through the kidneys, so dosage adjustment is required for patients with renal insufficiency.

Withdrawal Period:
- When used in breeding animals, Cefradine must follow the withdrawal period to avoid drug residues affecting food safety.

Veterinary API - For animal use only