Mavacamten (Camzyos, MYK-461)
Product Name: Mavacamten
Brand Names: Camzyos, MYK-461
CAS No.: 1642288-47-8
Molecular Formula: C15H19N3O2
Molecular Weight: 273.33 g/mol
Target/Mechanism: Allosteric modulator and inhibitor of cardiac myosin ATPase activity
Function: Reduces excessive actin-myosin cross-bridge formation, decreases hypercontractility, and shifts myosin toward an energy-sparing, super-relaxed state
Medical and Research Applications:
- Human Medicine: Prescribed to adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM) to improve functional capacity and relieve left ventricular outflow tract obstruction
- Research: Used in cardiovascular research for studying cardiac myosin regulation and hypertrophic cardiomyopathy
Mavacamten is a first-in-class cardiac myosin inhibitor used to treat symptomatic obstructive hypertrophic cardiomyopathy (HCM).
Brand Names: Camzyos, MYK-461
CAS No.: 1642288-47-8
Molecular Formula: C15H19N3O2
Molecular Weight: 273.33 g/mol
Target/Mechanism: Allosteric modulator and inhibitor of cardiac myosin ATPase activity
Function: Reduces excessive actin-myosin cross-bridge formation, decreases hypercontractility, and shifts myosin toward an energy-sparing, super-relaxed state
Medical and Research Applications:
- Human Medicine: Prescribed to adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM) to improve functional capacity and relieve left ventricular outflow tract obstruction
- Research: Used in cardiovascular research for studying cardiac myosin regulation and hypertrophic cardiomyopathy
Mavacamten is a first-in-class cardiac myosin inhibitor used to treat symptomatic obstructive hypertrophic cardiomyopathy (HCM).
| Short Description | API for HCM treatment, CAS 1642288-47-8, First-in-class cardiac myosin inhibitor |
|---|---|
| MOQ | 1 Piece |
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