Product Name: Trimethyl((2-(trifluoromethoxy)phenyl)ethynyl)silane
Catalog No.: AB20273
CAS No.: 1417508-42-9
Molecular Formula: C12H13F3OSi
Molecular Weight: 258.31 g/mol
InChI Key: IKHQUZFRZVDGPY-UHFFFAOYSA-N
SMILES: C[Si](C)(C)C#Cc1ccccc1OC(F)(F)F

Product Description:
This compound is Trimethyl((2-(trifluoromethoxy)phenyl)ethynyl)silane, a fluorinated organosilicon building block used primarily in advanced medicinal chemistry and materials science research. It functions as a protected terminal alkyne precursor. The trimethylsilyl (TMS) group can be selectively cleaved to yield 1-ethynyl-2-(trifluoromethoxy)benzene, which is widely utilized in click chemistry, Sonogashira cross-coupling reactions, and the incorporation of the metabolically stable trifluoromethoxy (-OCF3) group into pharmaceutical scaffolds.

Chemical Specifications:
- Product Name: Trimethyl((2-(trifluoromethoxy)phenyl)ethynyl)silane
- CAS Registry Number: 1417508-42-9
- Molecular Formula: C12H13F3OSi
- Molecular Weight: 258.31 g/mol
- InChI Key: IKHQUZFRZVDGPY-UHFFFAOYSA-N
- SMILES: C[Si](C)(C)C#Cc1ccccc1OC(F)(F)F

Applications:
- Advanced medicinal chemistry
- Materials science research
- Click chemistry
- Sonogashira cross-coupling reactions
- Incorporation of trifluoromethoxy (-OCF3) group into pharmaceutical scaffolds
- Protected terminal alkyne precursor

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